Organelle Network Communication


Overview

To elucidate mechanisms by which mitochondria-derived metabolites regulate physiological processes.
Specific aims are,

  • To dissect the functions of mitochondria-derived metabolites in regulation of aging and immune response, and signaling networks for cross-talks between mitochondria and other cellular organelles
  • To identify novel regulatory factors in differentiation and function of regulatory T cells through controlling mitochondrial metabolism
  • To characterize interplay between mitochondrial folate metabolism and cytoplasmic protein synthesis using formylmethionine, and their biological significance

    Participating Faculty